Guide for precise dosage control of granular products

　　I. Core Influencing Factors and Dosage Adjustment
　　Age and Weight
　　Children: Dosage must be calculated strictly according to weight. For example, the dosage of pediatric expectorant and cough suppressant granules should be given in layers based on age and weight (e.g., for a 5-year-old child weighing 20 kg, the daily dosage is 10-20 grams)23. Anesthesiologists commonly use the formula “milligrams/kilogram of body weight” to calculate the initial dose and adjust it dynamically according to vital signs.
　　Adults: Refer to the regular dosage in the instructions (e.g., Qingkailing granules, 1-2 packets per dose for adults), but those with higher weight may need to increase the dosage appropriately.
　　Severity of Illness
　　Mild cases: Reduce the dosage (e.g., for mild cases, Xiaor Jinye Baidu Granules are given twice daily, 0.5-1 gram per dose).
　　Severe cases: Increase the dosage appropriately (e.g., for severe cases, Qingkailing granules can increase the frequency of administration, but this requires a doctor's guidance).
　　Drug Composition and Dosage Form
　　Toxicity/Special Components: Granules containing poppy husk and ephedra should be used for a short period to avoid dependence or worsening hypertension3.
　　Differences in Dosage Forms: The effective ingredient content of lactic acid bacteria granules from different brands varies (e.g., for children, 0.5-1 gram/kg/day, divided into 3 doses).
　　II. Special Populations and Medication Standards
　　Children and the Elderly
　　Jinye Baidu granules should be used cautiously in children under 3 years old. It is recommended to dilute and administer in divided doses (e.g., 0.5-1 gram per dose for 6-month- to 3-year-olds).
　　Due to decreased metabolic capacity in the elderly, the dosage needs to be reduced (e.g., Qingkailing granules should be halved for those with impaired liver and kidney function).
　　Chronic Diseases and Contraindicated Populations
　　Impaired Liver and Kidney Function: Reduce the dosage of acetaminophen granules to avoid toxic accumulation;
　　Pregnant/Lactating Women: Avoid using blood-activating granules (e.g., Mudan granules);
　　Diabetic Patients: Choose sugar-free dosage forms (e.g., sugar-free Ganmao Qingre granules).
　　III. Administration and Dosage Optimization
　　Time and Administration Method
　　Taking after meals reduces gastrointestinal irritation (e.g., lactic acid bacteria granules should be taken after meals).
　　Traditional Chinese medicine granules should be dissolved in 40-50℃ warm water to avoid high temperatures destroying the efficacy (e.g., Jinye Baidu granules).
　　Dynamic Adjustment and Monitoring
　　After the initial dose, blood pressure, heart rate, and other indicators should be monitored (e.g., dynamic adjustment of anesthetic drugs);
　　Those taking medication long-term should have regular follow-up checkups (e.g., monitoring iron metabolism for Jianpi Shengxue granules).
　　IV. Summary of Dosage Adjustment Principles
　　Prioritize Formula Calculation: Preliminary estimation based on “weight × unit dose” (e.g., 0.5-1 gram/kg/day for children);
　　Individualized Adjustment: In combination with physique (reduced dosage for weak individuals), drug interactions (e.g., Montmorillonite powder should be taken separately from other medications);
　　Safety Bottom Line:
　　The single dose for children should not exceed 1/3-1/2 of the adult dose;
　　Seek medical attention immediately if symptoms persist for more than 3 days or if there is a high fever (>38.5℃).
　　Summary: The dosage of granules needs to be precisely controlled by comprehensively considering age, weight, condition, and drug characteristics. For children and special populations, it is preferable to calculate according to the formula and adjust based on individual differences. Strictly follow the instructions for administration (e.g., water temperature, administration time), and avoid increasing or decreasing the dosage on your own.